The treatment process

In the Radiosurgery Center in Debrecen, recently, new sources have been installed in the treatment device. With these treatments usually take between 20-40 minutes. This can vary depending on the type and size of the lesion, in some cases, can be up to 1.5-2 hours.
The procedure involves preparations that require a one-night hospital stay, and after the treatment, the patient can only be discharged with an escort.
Accommodation is available for the escorts at the clinic or in the city and the cost involved are agreed with everyone beforehand. If the patient has a valid health insurance, the travel costs may be reimbursed.

The day before treatment: a new MR scan is needed for accurate targeting

The day before the treatment, the patient is admitted to the Neurosurgery Department, where an MRI scan is taken. It is required for the preparation for planning the radiosurgical procedure.
A combined MRI-CT image is generated with the use of a contrast-enhanced CT scan on the day of the treatment to image the lesions in as much detail as possible. The combined image is used to define the spherical target irradiation areas of the treatment. The patient needs to spend the night at the hospital, so that preparations can begin early in the morning on the day of the treatment.

Preparation: frame attachment to ensure secure positioning of the head

Early in the morning on the day of the treatment, the nurse specialist of the Gamma Radiosurgery Center places a cannula in the arm of the patient for the contrast-enhanced CT scan.
The patient is only allowed to drink noncarbonated water from the morning on because the treatment needs to be done on an empty stomach.
To ensure accurate targeting, the head of the patient is securely fixed to the treatment device so that the gamma rays only reach predetermined locations of the lesion.
The fixation is ensured with a stereotaxic frame, which also serves as a 3-dimensional coordinate system for radiation surgery planning.
The contrast-enhanced CT scan for radiation surgery planning is already taken with the frame attached to the head of the patient, therefore the frame attachment is done in the CT operator room of the Department of Neurosurgery.
The frame is attached to the skull at four points, on two sides of the back of the head and two sides of the forehead. A local anesthetic is applied before the application of the fixation screws through the skin. After the frame is attached, a feeling of tightness might occur and disappears later. After the contrast CT scan, the patient is transferred by a local ambulance to the Gamma Radiosurgery Center.

Irradiation planning: the work of a team of dedicated professionals

The precision part of the procedure is the irradiation planning, which is done jointly by the neurosurgeon, the radiotherapist, and the radiation physicist. The neurosurgeon designs the course of the treatment using a dedicated computer to determine the 3-dimensional coordinates of the target area in relation to the stereotactic frame on the head of the patient. The same procedure defines the size of the target area and the radiation dose to be delivered during the treatment. The physicist confirms the coordinates and the dose rate to ensure the accuracy of the procedure. The planned dose depends on the histology of the disease, the size and location of the area to be treated, and the dose delivered in potential previous radiation treatments. Radiation planning takes about half an hour, during which time the patient is in the relaxation room with their escort.

Treatment procedure: in complete safety and without pain

Once the planning is complete, the patient is escorted to the air-conditioned treatment room, where they are placed on the radiosurgery equipment.
The rotating radiosurgery system for radiation surgery resembles in its geometry to an MRI machine. The frame attached to the skull of the patient is inserted into the frame holder to prevent the head from moving during the treatment; and to ensure that the radiation beams converge precisely on the target area to initiate the process of tumor tissue necrosis.
During the treatment, the patient is alone in the treatment room, but they are constantly monitored by video cameras and can communicate with the personnel via a built-in microphone. For the the complete treatment of the lesion, the machine might have to be repositioned several times during the procedure. During these times, several staff members assist the patient to prepare for the next phase of the procedure.

Completion of the treatment: frame removal and monitoring

At the end of the treatment, the frame is removed, and the small wounds are treated with a bandage and a covering band. The patient is provided information on the date and procedure of the follow-up diagnostic imaging. At this point, the patient is allowed to eat, and after a few hours of observation, in most cases, is discharged home the same day. For the discharge, an escort needs to be present to ensure the safety of the patient leaving the center. After a day of rest at home, the patient can resume normal activities if other existing medical conditions allow.